MULTIMODAL ATLASES

Characterizing a single subject with multiple imaging devices clearly combines the strengths of each imaging modality.

• Nemestrina Monkey Brain Atlas
  The Monkey brain atlas combines PET, CT, MRI and high-resolution cryosection imagery to generate a co-registered, multimodality map of the Nemestrina monkey brain.
  
• Alzheimer's Disease Atlas
  A multi-modality atlas of the brain in Alzheimer's disease combines thousands of annotated structure models with MRI, PET, cryosection, histologic and biochemical data in a common coordinate space.
  
• Visible Human Project
  Two (male and female) cadavers were cryoplaned and imaged at 1.0 mm intervals, and the entire bodies were also reconstructed via 5,000 post mortem CT and MRI images. The resulting digital datasets represent over 15 gigabytes of image. Users interact with the data by browsing through axial, coronal and sagittal views and can annotate and retrieve images in common graphical formats for subsequent segmentation and analysis.
  
  While not an atlas per se, the Visible Human imagery has sufficient quality and accessibility to make it a test platform for developing methods and standards. The data has served as the foundation for developing related atlases of regions of the cerebral cortex, and high-quality brain models and visualizations.