The MAP atlas describes
the mouse central nervous system in detail within a well-defined
coordinate system. It also details the morphological variability
across subjects within this strain as well as across maturational
stages from in utero to adult. The data is comprised of in vivo
and post mortem images.
We are currently in the process of developing and validating the
tools necessary to visualize, measure, spatially normalize (deformation
correct) and map gene expression. In addition to these design-driven
goals, we are testing several hypotheses using the aforementioned
atlas and tools. The product of this effort is an atlas system
for the C57BL/6J mouse, tools for using the atlas system, and
evidence that enables the study of the linkage between brain mapping
and gene mapping. |