The Laboratory of Neuro Imaging is a large, comprehensive research enterprise working on imaging, mapping and modeling approaches to understand brain structure and function in health and disease. Its membership is multi-disciplinary, with faculty, students and staff from mathematics, physics, computer science, neuroscience, and related fields.
LONI has a large roster of projects that include: neurovascular coupling in animal models and humans, structural MRI studies of healthy and diseased animal and human subpopulations, histological characterization of the post-mortem brain in primates and humans, new methodologies in image analysis, informatics, and computational modeling and mapping.
Many projects complement one another. Numerous programs and projects have been developed with independent funding for each. Several can be related to the others such that results obtained from one project can be used as a test bed for another; tools developed in one project can be applied to neurobiological questions posed in separate projects, so that data and tools can be maximally utilized.
For more information about a particular grant, click on the link under the Grant Name column.
Grant Name |
Grant Title |
Grant Description |
| ADNI Grant |
Alzheimer's Disease Neuroimaging Initiative |
Creation of a database to study the progression from MCI to AD using serial MRI, PET, other biological markers, and clinical and neuropsychological assessments. |
| CCB Grant |
Center for Computational Biology |
The CCB has been established to develop, implement and test computational biology methods that are applicable across spatial scales and biological systems. |
| ICBM Grant |
International Consortium for Brain Mapping |
The ICBM is developing a probabilistic reference system for the human brain. It is composed of four core research sites, UCLA, Montreal Neurologic Institute, University of Texas at San Antonio, and the Institute of Medicine, Juelich/Heinrich Heine University, Germany. |
| LONIR Grant |
Laboratory of Neuro Imaging Resource |
The LONI Resource studies changing morphology using a multidimensional modeling environment with 3 spatial and 1 temporal dimensions. |
| MouseBIRN Grant |
Mouse Brain Imaging Research Network |
The Mouse Brain Imaging Research Network provides a test bed for the formulation of hardware, software, and protocols to effectively share and mine multi-scale structural and functional data and integrate these with genomic and gene expression data on the mouse brain. |
| NAMIC Grant |
National Alliance for Medical Imaging Computing |
The National Alliance for Medical Imaging Computing seeks to develop computational tools for the analysis and visualization of medical image data in a multi-institutional, interdisciplinary team of computer scientists, software engineers, and medical investigators . |
| NLM Grant |
A Multidimensional Alzheimer?s Disease Brain Atlas |
The NLM grant is looking at MRI, Cryotomographic and immunohistochemical analysis of plaques and tangles in dementia in order to create an atlas of Alzheimer?s disease. |
| OIS Grant |
Optical Intrinsic Signal Imaging of Cortical Spreading Depression |
Functional activation studies in health and disease often depend upon perfusion related signals to localize the source of brain activity. The OIS grant investigates perfusion related signals measured using Optical Intrinsic Signals (OIS), Near Infrared Spectroscopy (NIRS), functional Magnetic Resonance Imaging (fMRI) and Electroencephalography (EEG) during a variety of stimulus conditions. |
| Tools For Sharing Grant |
Collaborative Brain Mapping: Tools for Sharing |
The Tools grant focuses on pooling, managing and archiving data between institutions and analyzing the data using appropriate algorithms executed on distributed resources using open, interoperable and portable software tools. |
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