The goal of the mouse brain imaging research network (MBIRN) is to provide a test bed for the formulation of hardware, software, and protocols to effectively share and mine multi-scale structural and functional data and integrate these with genomic and gene expression data on the mouse brain. MBIRN has been constructed to enhance the productivity of two ongoing collaborations in basic mouse models of neurological and psychiatric disorders:

• Dopamine transporter (DAT) knockout mouse with marked alterations in the dopaminergic system, making it an ideal model for studies of schizophrenia attention-deficit hyperactivity disorder (ADHD), and substance abuse.
• Experimental allergic encephalomyelitis (EAE) mouse models (both chemically induced and transgenic) which undergo episodic weakness and demyelination characteristic of multiple sclerosis.