Data: a group of shapes from controls (G_Ctrl) and a group of shapes from patients (G_Pat): 1) Determine the Atlas from the control group (G_Ctrl)

2) at each point in each control shape (G_Ctrl): a) find difference vector from the shape to the Atlas (dilation) b) project this vector onto the atlas surface normal at that point c) append the magnitude of this projection to a list for this vertex 3) do (2) except for disease shapes G_Pat) 4) calculate a statistical test (T-Test, initally) comparing the two lists for significance (p-value) 5) assign this P-value to a copy of the atlas (p<0.05 is probably significant).

 2) at each point in each control shape (G_Ctrl):
    a) find difference vector from the shape to the Atlas (dilation)
    b) project this vector onto the atlas surface normal at that point
    c) append the magnitude of this projection to a list for this vertex
 3) do (2) except for disease shapes G_Pat)
 4) calculate a statistical test (T-Test, initally)  comparing the two lists for significance (p-value)
 5) assign this P-value to a copy of the atlas (p<0.05 is probably significant).