• UTHSC plans to replicate Zapala data with new microarray platform and include many organs-would like to see MBAT expanded to handle other organs

MBAT review:

• Start with review of GeneNetwork query, there's some mismatching with some of the structure names. For the newer datasets, the structures are being mapped as closely to BIRNLex as possible so the terms match the atlases. Currently, with GN, Steve's using a look-up table. Mapping of structures isn't quite right-send the tables to Rob, Allan, and Maryann
• Annotation information for genes: GN has a more complete annotation than that from Affymetrix. Best possibile solution would be to register these from the UTHSC database with the mediator. Jyl will talk to the BIRN CC group to look into it. Internet speed could be a problem?
• Return of Gene Expression data: No sorting on parameters yet, would prefer to do that on the server end. UTHSC has it implemented on AJAX, would their code be useful for UCLA?
• Review of Zapala/Barlow data: Steve hasn't yet implemented the information from the paper yet...be better to sort this data so it can be uploaded to the BIRN microarray database.
• Still unclear of how to change the display in relation to the sorting of information. Still struggling with how to present the data heirarchy
• Would like to have an average column for structures (based on features of the mouse)
• General layout, the scrolling through the return results is the most important at this point-try to get more column information in the view
• GUI stuff is time consuming, so it'd be good to get as much of the layout figured out as possible before changing-Steve and Rob will play around with potential layouts. Allan has a suggested layout he can send around and UCLA will also look into having Zai revisit it.
• Is it possible to add the ability to let the user adjust the settings they want? User would need a cookie
• UTHSC will be able to give new data for Illumina arrays for 10 new animals in the near future
• UTHSC is working on the punch method, this type of data would be ideal for trying to register spatially to an atlas
• UTHSC has data from GNF in an Excel Table. They will try to use the BIRN microarray DB to upload this data.
• Potential to upload many other datasets over the summer
• The BIRN microarray DB should be registered to the mediator-start migrating all GE data to this DB
• Also start migrating the "freely sharable" data to a new "account" that would allow the users to browse any sharable data by any group
• Sounds like the current server may not be adequate for our needs in the future. Jyl will talk to CC about moving it to a more appropriate server
• We should contact Stan Nelson to demo MBAT. He's part of the microarray consortium, also might be able to look at their DB structure for expansion of ours towards one that would fit our desired common data model. Allan will contact him