[Education]       [Research]       [Honors]       [Experience]       [Publications]       [Teaching]
Duygu Tosun
Post-doctoral Fellow
Laboratory of Neuro Imaging, Center for Computational Biology
University of California, Los Angeles
Address: 635 Charles E. Young Drive South
Suite 225
Los Angeles, CA, 90095-7334
Phone: +1.310.206.2101
Fax: +1.310.206.5518
Email: duygu.tosun@loni.ucla.edu
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Education   
  • Ph.D., Electrical and Computer Engineering (2005) Johns Hopkins University, Baltimore, Maryland, USA.
  • M.A., Mathematics (2003) Johns Hopkins University, Baltimore, Maryland, USA.
  • M.S.E., Electrical and Computer Engineering (2001) Johns Hopkins University, Baltimore, Maryland, USA.
  • B.Sc., Electrical and Electronics Engineering (1999) Bilkent University, Ankara, Turkey.
    • Research Interests    

    My research focuses on developing new mathematical and computational approaches for image processing and analysis with application in the area of computational medicine. This includes the analysis of medical images using concepts from digital signal processing, partial differential equations, differential geometry, Riemannian geometry, optimization theory, statistical modeling, as well as computational neuroscience. I am also interested in the performance analysis approach to access the precision and accuracy of the developed algorithms. These tools may be used in clinical settings to better assist prevention, differential diagnosis, and therapy of neurodevelopmental diseases.

    Research Projects    

  • Surface features to quantify the gyrification and fissurization of the cortex.
  • Spatial normalization of the cortical surfaces for population analysis.
  • Automated cortical feature extraction (e.g., sulcal regions, curves of sulcal fundi and gyral crown) to assist surface warping and shape analysis.
  • Fast marching methods for mapping the 3-D geometry of the cortex.
  • Differential diagnosis using cortical morphometry in Parkinson's plus syndromes: Progressive Supranuclear Palsy (PSP), Multiple system atrophy (MSA), and Idiopathic Parkinson's disease (IPD).
  • Validation of mapping and analysis methods.

    • Honors and Awards   
  • Best shape extraction tool, UCLA Laboratory of Neuroimaging, Center for Computational Biology, All-Hands Meeting, Malibu, California, USA, 2006.
  • François Erbsmann Prize, Information Processing in Medical Imaging (IPMI) Conference, Glenwood Springs, CO, July 2005.
  • Departmental Fellowship, Johns Hopkins University, Baltimore, Maryland, USA, 1999--2005.
  • Institute for Pure and Applied Mathematics Travel Grant for the summer school on "Mathematics in Brain Imaging", Los Angeles, California, USA, 2004.
  • Center for Imaging Science (CIS) Fellowship, Johns Hopkins University, Baltimore, Maryland, USA, 1999--2000.
  • Board of Trustees (merit-based) Fellowship, Bilkent University, Ankara, Turkey, 1995--1999.
  • Dean's Honor List, Bilkent University, Ankara, Turkey, 1995--1999.
  • Ranked in the top 0.01% in the nationwide university entrance exam, Turkey, 1995.
  • Ranked in the top 0.1% in Mathematics Individual Contest, European Council of International Schools (ECIS), Waterloo, Belgium, 1995.
  • Awarded the Certificate of Achievement in Physics Leagues, Turkish Science Foundation (TUBITAK), Ankara, Turkey, 1994.
    • Research Experience   
  • Postdoctoral Fellow - working with Drs. Arthur W. Toga and Paul M. Thompson, Center for Computational Biology, Laboratory of Neuro Imaging, Department of Neurology, David Geffen School of Medicine, Oct. 2005 - Present.
  • Visiting Scientist - working with Dr. Christian Barillot, Team VisAGeS (Vision, Action and Information Management System in Health), INRIA (National Institute of Research in Computer Sciences and Automation), Rennes, France, Oct. 2006 - Dec. 2006.
  • Research Assistant - to Dr. Jerry L. Prince, Image Analysis and Communications Lab, Department of Electrical and Computer Engineering, the Johns Hopkins University, Aug. 1999 - Sept. 2005.
    • Selected Publications    
    [1] Duygu Tosun, Allan L. Reiss, Agatha D. Lee, Rebecca A. Dutton, Ursula Bellugi, Albert M. Galaburda, Julie R. Korenberg, Debbie L. Mills, Arthur W. Toga, and Paul M. Thompson, "Use of Cortical Curvature Feature to Analyze Local and Regional Cortical Folding Complexity", NeuroImage, in revision.
    [2] Duygu Tosun and Jerry L. Prince, "A Geometry-Driven Optical Flow Warping for Spatial Normalization of Cortical Surfaces", IEEE Transactions on Medical Imaging, in revision.
    [3] Duygu Tosun and Jerry L. Prince, ``Cortical Surface Alignment Using Geometry Driven Multispectral Optical Flow'', Information Processing in Medical Imaging (IPMI), Colorado, USA, July 11-15, 2005.
    [4] Duygu Tosun, Maryam E. Rettmann, Daniel Q. Naiman, Susan M. Resnick, Michael A. Kraut, and Jerry L. Prince, "Cortical Reconstruction Using Implicit Surface Evolution: Accuracy and Precision Analysis", NeuroImage, Vol/Issue 29/3, pp. 838-852, Feb. 2005.
    [5] Duygu Tosun, Maryam E. Rettmann, Xiao Han, Xiaodong Tao, Chenyang Xu, Susan M. Resnick, Dzung L. Pham, and Jerry L. Prince, ``Cortical Surface Segmentation and Mapping'', NeuroImage Special Issue on IPAM Mathematics in Brain Imaging, Vol/Issue 23S1, pp. S108-S118,2004 (invited paper).
    [6] Duygu Tosun, Maryam E. Rettmann, and Jerry L. Prince, ``Mapping techniques for aligning sulci across multiple brains'', Medical Image Analysis, Vol/Issue 8/3, pp. 295-309, 2004 (invited paper).
    Teaching   
  • Guest Lecturer - Signaux et Images en Biologie et Médecine, coordinated by Christian Barillot, Université de Tours-Angers-Nantes-Rennes, France, Fall 2006.
  • Teaching assistant - Medical Imaging Systems, Dr. Jerry L. Prince, The Johns Hopkins University, USA, Spring-Fall 2000.
  • Teaching assistant - Digital Signal Processing, Dr. Howard L. Weinert, The Johns Hopkins University, USA, Fall 1999.
  • Lecturer - Operating Systems, Word Processing, and Spread-sheet Basics for High School Students, Organized by Computer Literacy Program, Bilkent University Community Service Program, 1996-1998
    • last updated: 15.02.2007