| AD PATIENTS COMPENSATE WITH OTHER
BRAIN AREAS
Canadian researchers found that people with early-stage Alzheimer
disease can use other areas of their brain to pass memory tests.
Dr. Cheryl Grady, a senior scientist with The Rotman Research
Institute at Baycrest Centre for Geriatric Care, explained,
"We found that patients who were able to recruit the prefrontal
cortex of the brain 'to a greater degree' than other patients,
performed more accurately on memory tests."
The study is published in the February 1, 2003 issue of the
Journal of Neuroscience.
To read the full story go to sciencedaily.com
and news.bbc.co.uk.
MOBILE PHONES AND AD
Researchers from Lund University Hospital in Sweden say that
there may be a link between the use of mobile phones and the
early onset of Alzheimer's disease.
The controversial study looked at the effects of radiation
on laboratory rats, who were bombarded with radiation equivalent
to that from mobile phones.
Professor Leif Salford said, "We have already shown that
mobile radiation can allow harmful proteins and toxins through
the blood-brain barrier in rats. Now we see a significant degree
of damage to neurons in the brains of what you could call adolescent
rats."
To read the full story go to itv.com.
CAREGIVERS AT GREATER RISK OF HEART PROBLEMS
A University of California, San Diego, study found that the
stress of caring for a loved one with Alzheimer's disease may
place the caregiver at greater risk of heart problems.
The researchers collected information from 54 men and women
providing home care for a spouse with Alzheimer's disease.
They found higher incidence of blood clotting indicator which
may predict heart attacks and other coronary problems.
To read the full story go to healthcentral.com.
TENNESSEE CAREGIVER TELECONFERENCE
Marcia Wall, director of the Alzheimer's Association of Highland
Rim, says that most people are not familiar with the stress
on caregivers, stress that can decrease the entire household's
quality of life.
So on Feb. 11 from 7 to 8 p.m., the Alzheimer's Association
and Homewood Residence will host a teleconference that focuses
on bathing, dressing and toileting. At that time, participants
may call (800) 789-6311 and request to join the Alzheimer's
teleconference.
For more informatioj go to zwire.com.
LOW TESTOSTERONE LINKED TO DEMENTIA
An Australian study suggests that men with low levels of testosterone
may be at risk of developing brain diseases like dementia and
Alzheimer's later in life.
The research was based on 100 men between the ages of 29 and
80 with low levels of testosterone. Ninety-six per cent of them
went on to experience "loss of interest mentally and loss
of motivation" and 85 per cent suffered memory loss, lapses
in concentration and loss of mental clarity.
The findings follow a recent conference in London which examined
the relationship between the male hormone and the brain, and
the potential role of testosterone in preventing dementia.
To read the full story go to hearldsun.news.com.
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AD HOLOCAUST SURVIVORS RELIVE OLD
HORRORS
White lab coats, restraints and locked doors, antiseptic smells,
people yelling in pain could spark vivid flashbacks for Jews
with Alzheimer's disease who endured Nazi cruelty during The
Holocaust.
The hoarding of food in pockets and drawers and under mattresses,
as if hiding it from soldiers, is a common occurrence, said
David Bier of the Council for Jewish Elderly. If a worker tries
to take the food away from them, they often lash out.
The Holocaust Community Services program visits nursing homes
in Chicago and the suburbs, giving history lessons and sensitivity
seminars. They train nursing home employees to understand what
Holocaust survivors may be going through and offer tips on how
to avoid triggering bad memories and violent reactions.
To read the full story go to sanluisobispo.com.
BRAIN CHANGES IN AD MOUSE
Jeffrey Redwine of Neurome, Inc. and colleagues, have published
a paper describing regional brain volumetric changes in the
PDAPP mouse model of Alzheimer's disease using high-resolution
magnetic resonance microscopy (MRM).
The measurements taken revealed that reduced volume in certain
regions of the brain can be detected by MRM prior to the deposition
of beta-amyloid, the protein that forms thick deposits, or plaques,
in the brains of people with Alzheimer's disease.
Floyd Bloom, M.D., of The Scripps Research Institute commented,
"We were quite surprised that pathology was evident this
early in the animal's life. This is important since it suggests
that at least in this animal model, therapeutic interventions
can and should be tested in fairly young animals -- well before
the appearance of more advanced reflections of Alzheimer's disease
pathology."
To read the full story go to northernlight.com.
PFIZER, YALE TEAM UP FOR DRUG RESEARCH
Pfizer Inc. and Yale University will collaborate on a new clinical
research center to study drugs for neurological disorders and
other diseases.
Pfizer will spend about $35 million to build the center where
its scientists will work with Yale School of Medicine researchers
to study high-tech scanning technologies that are used to track
the effects of new drugs in the body.
To read they full story go to northernlight.com.
MEMORY CONSTRUCTION
Professor Mark D'Esposito and colleagues of UC Berkeley has
verified that the same area of the human brain is used in the
development of two separate types of memory – working and
long-term memory.
D'Esposito explained that working memory holds and processes
information for a short period of time, like the seven digits
of a phone number being dialed. Once information is transferred
to long-term memory it can be recalled after the subject has
moved on to other tasks.
The researchers hope to use their discovery to help the elderly
and Alzheimer's patients with memory loss.
To read the full story go to dailycal.org.
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