Copyright 2001 U.P.I. United Press International

November 5, 2001, Monday 02:18 AM Eastern Time

SECTION: WEATHER

LENGTH: 794 words

HEADLINE: Stories from Modern Science...from UPI

BYLINE: By ALEX CUKAN, UPI Science Writer

HOW GENES AFFECT BRAIN STRUCTURE

UCLA brain mapping researchers in California have created the first images to show how an individual's genes can influence brain structure and intelligence. Published in Nature Neuroscience, the findings offer new insight on how parents pass on personality traits and cognitive abilities, and how brain diseases run in families. The team found that the amount of gray matter in the frontal parts of the brain is determined by the genetic make-up of an individual's parents. Brain regions controlling language and reading skills were virtually identical in identical twins, who share exactly the same genes, while siblings showed only 60 percent of the normal brain differences. "This tight structural similarity in the brains of family members helps explain why brain diseases, including schizophrenia and some types of dementia, run in families," says Paul Thompson. "We were stunned to see that the amount of gray matter in frontal brain regions was strongly inherited, and also predicted an individual's IQ score." 0-